two and eight en · NOUN
Meanings
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(Cockney, slang) A state (of upset, worry).
I didn't get home until two in the morning, and me missus got herself into a right two and eight over it!
Suddenly, to his horror, Mr Candy found himself in what Ma would have called a terrible two-and-eight.
1963, H. E. Bates, Oh! To be in England: