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Dictionary

Words, grammatical forms and meanings linked to the ontology.

sildenafil en · NOUN

Pronunciation

  • /sɪlˈdɛn.ə.fɪl/

Etymology

Probably from s(ulfon)yl + -dena- (“alteration of (pyrimi)dine”) + ph(en)yl.

Meanings

  1. (uncountable, usually) A drug that is used in the form of its citrate C₂₂H₃₀N₆O₄S·C₆H₈O₇ to treat erectile dysfunction in males, that by suppressing a phosphodiesterase enzyme also suppresses the enzyme's inhibitory effect on the hormone cyclic GMP, and that enables the cyclic GMP produced during sexual arousal to initiate the muscular and vascular changes which produce an erection. It is marketed under the trademarks Revatio and Viagra.
    • Ellis opens a file from his stack. In 1991, he says, Pfizer wanted to test the safety of what came to be known as sildenafil. 2017, David Friend, The Naughty Nineties:

Forms

SpellingFeaturesLabelsSource
sildenafils Number=Plur lexicographic

Deriveds

-afil · sildenafil citrate

Translations (4)

fi sildenafiili (Translations) · el σιλδεναφίλη (Translations) · cmn 西地那非 (Translations) · tr sildenafil (Translations)