proto-oncogene en · NOUN
Etymology
Etymology tree Proto-Indo-European *per-der.? Proto-Indo-European *per-der.? Proto-Indo-European *pér Proto-Indo-European *-o Proto-Indo-European *próder. Ancient Greek πρό (pró) Ancient Greek -ᾰτος (-ătos) Ancient Greek πρῶτος (prôtos) Ancient Greek πρωτο- (prōto-)lbor. English proto- Ancient Greek ὄγκος (ónkos)der. New Latin onco-der. English onco- English gene English oncogene English proto-oncogene From proto- + oncogene.
Meanings
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A gene, promoting the specialization and division of normal cells, that could become an oncogene due to mutation.
Typically, proto-oncogenes are normal cellular genes that, when activated by mutation or overexpression, promote cancer.
2010, Siddhartha Mukherjee, The Emperor of All Maladies, Fourth Estate (2011), page 534:
Forms
| Spelling | Features | Labels | Source |
|---|---|---|---|
| proto-oncogenes | Number=Plur | lexicographic | |
| protooncogene | alternative | lexicographic |
Deriveds
Relateds
oncoproteomics · oncoproteogenome · oncogenomic · oncogenomics · oncogenic · oncoproteomic · oncogenics · oncogenetic · oncologic · oncology · oncoproteogenomics · oncoprotein · oncoproteome · oncogenome · oncogenesis · oncological · oncogenetics · oncoproteogenomic · oncogene
Translations (5)
fi proto-onkogeeni (gene promoting the specialization and division of normal cells that could become an oncogene due to mutation) · hu protoonkogén (gene promoting the specialization and division of normal cells that could become an oncogene due to mutation) · fi esisyöpägeeni (gene promoting the specialization and division of normal cells that could become an oncogene due to mutation) · fr proto-oncogène (gene promoting the specialization and division of normal cells that could become an oncogene due to mutation) · it protooncogene (gene promoting the specialization and division of normal cells that could become an oncogene due to mutation)