Dictionary

progeria en · NOUN

Pronunciation

• /pɹoʊˈd͡ʒɪ(ə)ɹiə/

Etymology

From Ancient Greek προγήρως (progḗrōs, “prematurely old”) + -ia.

Meanings

1. (countable, uncountable) An extremely rare genetic condition wherein symptoms resembling aspects of aging are manifested at an early age.
   • Hutchinson Gilford progeria syndrome (progeria) is a rare childhood disease, affecting 1 in 4 million births worldwide (Hennekam, 2006) and recapitulates certain aspects of the normal aging process at an accelerated rate. 2015, Ingrid A. Harten, Michelle Olive, Thomas N. Wright, “16: Vascular Disease in Hutchinson Gilford Progeria Syndrome and Aging: Common Phenotypes and Potential Mechanisms”, in Matt Kaeberlein, George Martin, editors, Handbook of the Biology of Aging, 8th edition, page 434:
   • Hutchinson-Gilford progeria is a syndrome commonly characterized by accelerated aging. Children affected by progeria have a life expectancy of approximately 13 years. Progeria results from damage to the LMNA gene that codes for the protein lamin A. 2007, Carie Ann Braun, Cindy Miller Anderson, Pathophysiology: Functional Alterations in Human Health, page 436:
   • Hutchinson–Gilford syndrome or progeria (derived from pro, before, and geras, old age) is characterized by premature ageing (Fig. 18.1) and the early onset of age-related symptoms such as joint restriction and cerebral and myocardial infarction. Progeria occurs in about one in eight million people (DeBusk, 1972), but the true incidence may be somewhat higher (Sarkar and Shinton, 2001). 2004, E. S. Roach, “18: Hutchinson-Gilford progeria syndrome”, in E. Steve Roach, Van S. Miller, editors, Neurocutaneous Disorders, page 150:

Forms

Deriveds

progeric · pseudoprogeria · progerin · progeroid

Relateds

Werner syndrome

Synonyms

Hutchinson-Gilford progeria syndrome (genetic condition exhibiting symptoms of aging at an early age) · Benjamin Button disease (genetic condition exhibiting symptoms of aging at an early age) · Hutchinson–Gilford syndrome (genetic condition exhibiting symptoms of aging at an early age) · Hutchinson-Gilford progeria (genetic condition exhibiting symptoms of aging at an early age)

Translations (12)

es progeria (genetic condition wherein symptoms resembling aging are manifested at an early age) · cmn 早老症 (genetic condition wherein symptoms resembling aging are manifested at an early age) · kk прогерия (genetic condition wherein symptoms resembling aging are manifested at an early age) · cmn 早衰症 (genetic condition wherein symptoms resembling aging are manifested at an early age) · hi प्रोजेरिया (genetic condition wherein symptoms resembling aging are manifested at an early age) · he פרוגריה (genetic condition wherein symptoms resembling aging are manifested at an early age) · pt progeria (genetic condition wherein symptoms resembling aging are manifested at an early age) · fi progeria (genetic condition wherein symptoms resembling aging are manifested at an early age) · ja 早老症 (genetic condition wherein symptoms resembling aging are manifested at an early age) · fr progéria (genetic condition wherein symptoms resembling aging are manifested at an early age) · pt progéria (genetic condition wherein symptoms resembling aging are manifested at an early age) · it progeria (genetic condition wherein symptoms resembling aging are manifested at an early age)