Dictionary

phlebotonic en · ADJ

From phlebo- + tonic.

Affecting the tone of veins; that is, affecting the muscle tone of the smooth muscle in the walls of veins, thus influencing blood flow within the lumen.

Spelling	Features	Labels	Source
most phlebotonic	Degree=Sup		lexicographic
more phlebotonic	Degree=Cmp		lexicographic

From phlebo- + tonic.

A substance (especially a drug) that is phlebotonic; a drug that modifies the tone of vein walls to treat venous insufficiency causing venous ulcers, hemorrhoids, or varicose veins.
- Phlebotonics are a heterogeneous class of drugs used to treat haemorrhoidal disease in the less severe stages of first and second-degree haemorrhoids, and during the thrombosis episodes. Although their true mechanism of action has not been well established, they are associated with strengthening of blood vessel walls, increasing venous tone, lymphatic drainage and normalizing capillary permeability. We considered twenty four studies for inclusion in this review. This review identified twenty randomised controlled trials enrolling a total of (2334) participants which compared an intervention using phlebotonics with a control intervention. 2012, Perera N, Liolitsa D, Iype S, Croxford A, Yassin M, Lang P, Ukaegbu O, van Issum C, “Phlebotonics for haemorrhoids”, in Cochrane Database of Systematic Reviews, volume 15, number 8, →DOI, →PMID, page CD004322:

Spelling	Features	Labels	Source
phlebotonics	Number=Plur		lexicographic