Dictionary

pharmacomodulation en · NOUN

Etymology

From pharmaco- + modulation.

Meanings

1. (countable, uncountable) The modification of existing pharmaceuticals by replacing substituents etc
   • Interestingly, the p-chloro- and p-trifluoromethyl-phenyl monophenols 10 and 11 retained activity (EC 50 = 4.0 ± 1.4 μM and 12.4 ± 6.9 μM, respectively) with an excellent selectivity versus proliferating TG1 GSCs, suggesting that pharmacomodulation is possible at this position. 2015 August 14, “Chemical Library Screening and Structure-Function Relationship Studies Identify Bisacodyl as a Potent and Selective Cytotoxic Agent Towards Quiescent Human Glioblastoma Tumor Stem-Like Cells”, in PLOS ONE, →DOI:

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