pathoprogression en · NOUN
Etymology
From patho- + progression.
Meanings
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(uncountable) The progression of a disease
This leads us to speculate that lysosomal impairment due to diminished GCase expression and enzyme activity as shown in AD could also affect cell-to-cell transmission of Aβ aggregates and the pathoprogression of AD.
2015 December 3, “Lysosomal Enzyme Glucocerebrosidase Protects against Aβ 1-42 Oligomer-Induced Neurotoxicity”, in PLOS ONE, →DOI: