paroxysmal nocturnal hemoglobinuria en · NOUN
Meanings
- (uncountable) A rare, acquired blood disorder in which a mutation in the PIGA gene causes red blood cells to lack protective surface proteins, making them vulnerable to complement-mediated destruction, leading to hemolysis, anemia, dark urine, and increased risk of blood clots.
Forms
| Spelling | Features | Labels | Source |
|---|---|---|---|
| paroxysmal nocturnal haemoglobinuria | UK, alternative | lexicographic | |
| PNH | Abbr=Yes | lexicographic |
Relateds
paroxysmal cold hemoglobinuria