Dictionary

oncometabolite en · NOUN

Etymology

From onco- + metabolite.

Meanings

1. Any metabolite that is associated with a cancer
   • Due to this pleiotropic function for dysregulating biological events, 2-HG is regarded as an oncometabolite that exerts tumor-inducing actions, and searches for IDH gene mutations have been performed in various types of malignancies [1 ,2 ]. 2015 July 11, “Mutant IDH1 Dysregulates the Differentiation of Mesenchymal Stem Cells in Association with Gene-Specific Histone Modifications to Cartilage- and Bone-Related Genes”, in PLOS ONE, →DOI:

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