nonionizable en · ADJ
Etymology
From non- + ionizable.
Meanings
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(not-comparable) Not ionizable.
In fact, dutasteride has nonionizable groups with the pH-independent solubility profiles (pH 1–12). 21 However, the physical mixture exhibited an extremely low dissolution of less than 5% in all types of dissolution medium due to the poor solubility of dutasteride.
2015 June 23, In-hwan Baek et al., “Design of a gelatin microparticle-containing self-microemulsifying formulation for enhanced oral bioavailability of dutasteride”, in Drug Design, Development and Therapy, volume 9, →DOI: