nonactivatable en · ADJ
Etymology
Etymology tree Proto-Indo-European *né Proto-Germanic *ne Proto-Indo-European *ís? Proto-Indo-European *h₁óynos Proto-Germanic *ainaz Proto-Germanic *nainaz Proto-West Germanic *nain Old English nān Middle English non ▲ Old English nān Old English nān- Middle English non- English non- Proto-Indo-European *h₂eǵ- Proto-Indo-European *-eti Proto-Indo-European *h₂éǵeti Proto-Italic *agō Latin agō Proto-Indo-European *-wós Proto-Indo-European *-iHwósder. Latin -īvus ▲ Ancient Greek ἐνεργητῐκός (energētĭkós)sl. Latin āctīvusbor. Old French actifbor. Middle English actyf English active Proto-Indo-European *-h₂ Proto-Indo-European *-éh₂ Proto-Indo-European *-tós Proto-Indo-European *-eh₂tos Proto-Italic *-ātos Latin -ātuslbor. English -ate English activate Proto-Indo-European *-dʰlom Proto-Italic *-ðlom Proto-Italic *-ðlis Latin -bilis Latin -ābilis Old French -ablebor. Middle English -able English -able English activatable English nonactivatable From non- + activatable.
Meanings
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(not-comparable) Not activatable.
Fig. 15.8 Comparison of imaging with MPO(Gd) and a nonactivatable analog.
2011, James C. Carr, Timothy J. Carroll, Magnetic Resonance Angiography: Principles and Applications, page 209:Tonic block of sodium channels by many local anesthetics, a partial block that is presence in the absence of hig-frequency activation, appears to be caused by a selective action of the drug on a nonactivatable form of closed channels (COURTNEY 1975) .
2012, Gary R. Strichartz, Local Anesthetics, page 77:In native Torpedo membranes, the nAChR exists in equilibrium between activatable resting and nonactivatable desensitized states, with the equilibrium strongly favoring the desensitized conformation (roughly 80:20 resting:desensitized) (Boyd & Cohen, 1980; Heidmann & Changeux, 1979).
2017, John E. Baenziger, Jaimee A. Domville, J.P. Daniel Therien, “The Role of Cholesterol in the activation of nAChRs”, in Sterol Regulation of Ion Channels, page 104: