neurotoxicity en · NOUN
Pronunciation
- (US) audio
Etymology
Etymology tree Proto-Indo-European *(s)neh₁- Proto-Indo-European *-wr̥ Proto-Indo-European *snéh₁wr̥der. Ancient Greek νεῦρον (neûron) Ancient Greek νευρο- (neuro-)der. English neuro- Ancient Greek τοξῐκός (toxĭkós) Ancient Greek τοξικόν (toxikón)der. Latin toxicum Proto-Indo-European *-kos Proto-Italic *-kos Latin -cus Latin toxicusbor. French toxiquebor. English toxic Proto-Indo-European *-teh₂ Proto-Indo-European *-ts Proto-Indo-European *-teh₂ts Latin -itāsder. Old French -itebor. Middle English -ite English -ity English toxicity English neurotoxicity From neuro- + toxicity.
Meanings
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(countable, uncountable) The state or property of being neurotoxic.
It has been shown that PQQ could be involved in the treatment of neurological and psychical disorders. For example, it was demonstrated to have excellent neuroprotective efficacy in vitro and in vivo models of NMDAR-mediated or other neurotoxicant, such as methylmercury and 6-hydroxydopamine, induced neurotoxicity and electrical responses [4], to reduce the infarct size in animals with hypoxia and ischemia [5], to protect hippocampal neurons from the increase of the intracellular Ca²⁺ level and to be effective in an animal model of epilepsy [6].
2010 October 10, Yanyan Kong et al., “Preparation of 99mTc-PQQ and preliminary biological evaluation for the NMDA receptor”, in Journal of Radioanalytical and Nuclear Chemistry, volume 287, →DOI, archived from the original on 04 Apr 2025:
Forms
| Spelling | Features | Labels | Source |
|---|---|---|---|
| neurotoxicities | Number=Plur | lexicographic |
Translations (5)
el νευροτοξικότητα (the state or property of being neurotoxic) · pt neurotoxicidade (the state or property of being neurotoxic) · ga néarthocsaineacht (the state or property of being neurotoxic) · pl neurotoksyczność (the state or property of being neurotoxic) · es neurotoxicidad (the state or property of being neurotoxic)