nerve growth factor en · NOUN
Meanings
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(countable, uncountable) a functional protein complex required for the survival, growth and specialization of certain types of neurons in vertebrates.
They (trypsin-like serine proteases) are also thought to be involved in the processing or activation of other biologically important proteins such as nerve growth factor (NGF) and epidermal growth factor (EGF) (3–5).
1983, Philip N. Howles, Douglas P. Dickinson, Laura L. DiCaprio, Mary Woodworth-Gutai, Kenneth W Gross, “Use of a cDNA recombinant for the γ-subunit of mouse nerve growth factor to localize members of this multigene family near the TAM-1 locus on chromosome 7.”, in Nucleic Acids Research, 12, no. 6 26 March 1984: 2791:Nerve growth factor is the prototypical member of the neurotrophin family.
1999 Landreth, Gary E. Growth Factors. In: Siegel, George J.; et al. Basic Neurochemistry. Philadelphia: Lippincott–Raven Publishers; 1999 [cited 18 December 2009]. Available from: http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=bnchm&part=A1358#A1364
Forms
| Spelling | Features | Labels | Source |
|---|---|---|---|
| nerve growth factors | Number=Plur | lexicographic |
Coordinates
brain-derived neurotrophic factor · neurotrophin-3 · neurotrophin-4
Hypernyms
Meronyms
α-NGF · γ-NGF · β-NGF · β-nerve growth factor