Dictionary

myeloneuropathy en · NOUN

Pronunciation

• /ˈmaɪələʊnjʊˌɹɒpəθi/ (Received-Pronunciation)

Etymology

From myelo- + neuropathy.

Meanings

1. (countable, uncountable) A disease with the features of myelopathy (spinal cord disease) and neuropathy (peripheral nerve disease), which is sometimes caused by a deficiency of copper or vitamin B₁₂.
   • Diagnosis […] Myeloneuropathy, chronic, traumatic, probably due to injury of L-4, clinically complete motor wise below L-3 and sensory wise below L-3. 1966, Bulletin of Prosthetics Research, Washington, D.C.: Department of Medicine and Surgery, Veterans Administration, →OCLC, page 157:
   • A myeloneuropathy is caused by inactivation of vitamin B₁₂ by nitrous oxide. Patients with borderline vitamin B₁₂ deficiency who undergo anesthesia using nitrous oxide can also have a myeloneuropathy develop but more often megaloblastic anemia develops, whereas the chronic exposure of recreational users is more likely to cause myeloneuropathy without anemia. 2003, Friedrich von Rosen with John C. M. Brust, “Acute Intoxications”, in Thomas Brandt, Louis R. Caplan, Johannes Dichgans, H. Christoph Diener, Christopher Kennard, editors, Neurological Disorders: Course and Treatment, 2nd edition, Amsterdam: Academic Press, →ISBN, page 802:
   • The term tropical myeloneuropathies refers to several syndromes encountered in equatorial countries around the world. The syndromes are manifestations of lesions in the spinal cord and peripheral nerves, separately or together. These disorders have been long-standing public health problems. Some have been traced to specific causes, including infection with HTLV-I, or the chronic ingestion of cassava beans or lathyrogenic agents. Other exogenous toxins may play a role. In the past and perhaps still today, similar syndromes have been ascribed to nutritional deprivation. 2010, Lewis P. Rowland with Paul H. Gordon, “Hereditary and Acquired Spastic Paraplegia”, in Lewis P. Rowland, Timothy A. Pedley, editors, Merritt's Neurology, 12th edition, Philadelphia, Pa.: Lippincott Williams & Wilkins, →ISBN, page 382:
   • Copper deficiency has been associated with a clinical syndrome, myeloneuropathy. Radiographic changes resembling B₁₂ deficiency in the cervical spinal cord have been described. We present a case of copper deficiency myeloneuropathy, with cervical MR imaging findings resembling B₁₂ deficiency, which partially reversed following copper supplementation. 2006 November, B. P. Goodman with B. W. Chong, A. C. Patel, G. P. Fletcher, and B. E. Smith, “Copper Deficiency Myeloneuropathy Resembling B₁₂ Deficiency: Partial Resolution of MR Imaging Findings with Copper Supplementation”, in American Journal of Neuroradiology, volume 27, abstract, page 2112:

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