Dictionary

misreplicate en · VERB

Etymology

From mis- + replicate.

Meanings

1. (ambitransitive, of DNA) To make an error during replication.
   • During cell division there is a probability that either or both of the master replicons will misreplicate and one of the daughter cells will be missing a master copy. 1970, Michael Abercrombie, Jean Brachet, Thomas Joseph King, Advances in Morphogenesis - Volume 8, page 177:
   • Transcription errors cause a tector to misreplicate into a form symbiotic with living cells. 2011, Ian McDonald, Necroville:
   • It is important to realize that errors in protein synthesis may also result in altered DNA polymerase, which would misreplicate DNA, thereby injecting errors into the genome that would lead to clones of abnormal cells (Orgel, 1973). 2013, Edward Schneider, The Genetics of Aging, page 18:
   • Thus when the second master unit begins to misreplicate, then in cells that still possess both units, the rate of misreplication becomes the same for both master units, even though they were initially lost at different rates. 1973, Alfred Marlyn Elliott, Biology of Tetrahymena, page 354:

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