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Dictionary

Words, grammatical forms and meanings linked to the ontology.

misfold en · NOUN

Pronunciation

  • (Southern-England) audio
  • (Southern-England) audio
  • /ˈmɪsfoʊld/

Etymology

Etymology tree Proto-Indo-European *mey-? Proto-Indo-European *meyth₂-der. Proto-Germanic *missaz Proto-Germanic *missa- Proto-West Germanic *missa- Old English mis- Middle English mys- English mis- English fold English misfold From mis- + fold.

Meanings

  1. An incorrect or abnormal folding.

Forms

SpellingFeaturesLabelsSource
misfolds Number=Plur lexicographic

misfold en · VERB

Pronunciation

  • (Southern-England) audio
  • /mɪsˈfoʊld/
  • (Southern-England) audio

Etymology

Etymology tree Proto-Indo-European *mey-? Proto-Indo-European *meyth₂-der. Proto-Germanic *missaz Proto-Germanic *missa- Proto-West Germanic *missa- Old English mis- Middle English mys- English mis- English fold English misfold From mis- + fold.

Meanings

  1. (intransitive, of a protein or nucleic acid) To fold into an unusual or incorrect tertiary structure; misfolded proteins occur in various diseases, including amyloidoses and dementias, although the question of causation versus consequence is not yet definitively answered for dementias.
    • The prionopathies are best known among the neurodegenerative diseases for their ability to misfold, self-propagate, and infect other organisms. 2021 March 1, Anderson, K.N.; Overcast, W.B.; Brosch, J.R.; Graner, B.D.; Veronesi, M.C., “Prionopathies and Prionlike Protein Aberrations in Neurodegenerative Diseases”, in American Society of Neuroradiology, volume 11, number 2, →DOI, pages 127-148:

Forms

SpellingFeaturesLabelsSource
misfolded Tense=Past, VerbForm=Part lexicographic
misfolded Tense=Past lexicographic
misfolds Number=Sing, Person=3, Tense=Pres lexicographic
misfolding Tense=Pres, VerbForm=Part lexicographic