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Dictionary

Words, grammatical forms and meanings linked to the ontology.

metyrapone en · NOUN

Pronunciation

  • /mɪˈtɪ.ɹə.pəʊn/ (Received-Pronunciation)
  • /mɪˈtʌɪ.ɹə.pəʊn/ (Received-Pronunciation)
  • /məˈtɪɹ.əˌpoʊn/ (General-American)

Etymology

From meth- + (dip)yr(idyl) + -a- + (pro)p(an)one.

Meanings

  1. (uncountable) A compound that inhibits the enzyme 17β-hydroxylase and prevents synthesis of glucocorticoids and mineralocorticoids by the adrenal gland, used chiefly for assessment of feedback control of the hypothalamic–pituitary axis in adrenal disease, and sometimes in the treatment of Cushing's syndrome and resistant edema; 2-methyl-1,2-di-3-pyridyl-1-propanone, C₅H₄N·CO·C(CH₃)₂·C₅H₄N.