methotrexate en · NOUN
Pronunciation
- /ˌmɛθ.əˈtɹɛk.seɪt/ (Received-Pronunciation)
- /ˌmɛθ.əˈtɹɛkˌseɪt/ (General-American)
- /ˌmiː.θəˈtɹɛk.seɪt/ (Received-Pronunciation)
Etymology
Probably from metho- + tre- (“alteration of pteridine”) + (carbo)x(yl)ate.
Meanings
-
(countable, uncountable) An antimetabolite and antifolate drug used in treatment of cancer, autoimmune diseases, and ectopic pregnancies.
One group would be treated with intensive methotrexate dosing, while the other group would be treated with milder and less intensive dosing.
2010, Siddhartha Mukherjee, The Emperor of All Maladies, Fourth Estate, published 2011, page 133:
Forms
| Spelling | Features | Labels | Source |
|---|---|---|---|
| MTX | Abbr=Yes | lexicographic | |
| methotrexates | Number=Plur | lexicographic |
Deriveds
Synonyms
Translations (6)
hu metotrexát (antimetabolite and antifolate drug) · kk метотрексат (antimetabolite and antifolate drug) · fr méthotrexate (antimetabolite and antifolate drug) · es metotrexato (antimetabolite and antifolate drug) · de Methotrexat (antimetabolite and antifolate drug) · it metotrexato (antimetabolite and antifolate drug)