methoctramine en · NOUN
Pronunciation
- /mɛθˈɑk.tɹəˌmiːn/ (General-American)
Etymology
Probably from meth(ylene) + oc(tane) + (te)tr(a)amine.
Meanings
-
(uncountable) A polymethylene tetraamine that acts as a muscarinic antagonist
It has been recently demonstrated that hyperexcitation can be neuroprotective for SOD1 Mns and that the muscarinic receptor antagonist, methoctramine enhanced the accumulation of misfolded SOD1 proteins in these neurons.
2015 August 26, “Age-Related Changes in Pre- and Postsynaptic Partners of the Cholinergic C-Boutons in Wild-Type and SOD1 G93A Lumbar Motoneurons”, in PLOS ONE, →DOI: