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Dictionary

Words, grammatical forms and meanings linked to the ontology.

mesothelin en · NOUN

Etymology

From mesothelial + -in.

Meanings

  1. (uncountable) A protein found in mesothelial cells and overexpressed in several human tumors.
    • CAR T cells targeting vascular endothelial growth factor receptor 2 (VEGFR2), epidermal growth factor receptor variant III (EGFRvIII), and mesothelin are being tested in patients with glioblastoma, pancreatic, ovarian and mesothelioma cancers. 2015 July 15, “IGF1R- and ROR1-Specific CAR T Cells as a Potential Therapy for High Risk Sarcomas”, in PLOS ONE, →DOI: