macrothrombocytopenia en · NOUN
Etymology
From macro- + thrombocytopenia.
Meanings
-
(countable, uncountable) A form of thrombocytopenia characterised by unusually large platelets.
Absence or dysfunction of GPIb-V-IX results in the Bernard-Soulier Syndrome, a bleeding disorder characterised not only by impaired platelet adhesion, but also by macrothrombocytopenia, due to a disturbed link between the GPIb-V-IX complex and the underlying cytoskeleton during platelet and/or MK formation.
2015 July 16, “Artificial MiRNA Knockdown of Platelet Glycoprotein lbα: A Tool for Platelet Gene Silencing”, in PLOS ONE, →DOI:
Forms
| Spelling | Features | Labels | Source |
|---|---|---|---|
| macrothrombocytopenias | Number=Plur | lexicographic |