Dictionary

ketol en · NOUN

Pronunciation

• /ˈkiː.tɒl/ (Received-Pronunciation)
• /ˈkiː.təʊl/ (Received-Pronunciation)
• /ˈki.toʊl/ (General-American)
• /ˈki.tɑl/ (General-American)
• (Southern-England) audio

Etymology

Blend of ketone + indol.

Meanings

1. A hydroxyketone (e.g., an acyloin).
   • 1962, James A. Moore, Erich Heftmann, Chapter 2: Chemistry of the adrenocortical steroids, Helen Wendler Deane, The Adrenocortical Hormones, Part 1, Springer-Verlag, page 221, The 21-hydroxyl group in the α-ketol side chain is very easily esterified, and in many of the synthetic routes leading to these side chains the ketol acetate is still formed.
   • Consider the enolization (Scheme 3.26) of the methyl ester of acetoacetic acid, a reaction involving ketol-enol tautomerism. 2010, Daniel L. Purich, Enzyme Kinetics: Catalysis and Control, Elsevier, Academic Press, page 201:
   • The steroid acetates are stable derivatives, having the desirable property that the electron-capture detector (ECD) selectively responds to acetyl derivatives of α-ketols [958]. 2011, Erich Heftmann, Chromatography of Steroids, Elsevier, page 29:

Forms

Deriveds

methylketol · ketolated · ketolation · ketolic

Hyponyms

α-hydroxy ketone · β-hydroxy ketone