isotretinoin en · NOUN
Pronunciation
- /ˌʌɪ.sə(ʊ).tɹəˈtɪn.əʊ.ɪn/ (Received-Pronunciation)
- /ˌaɪ.soʊˈtɹɛt.ɪˌnoʊ.ɪn/ (General-American)
Etymology
From iso- + tretinoin.
Meanings
- (uncountable) A cis isomer of retinoic acid that is a synthetic derivative of vitamin A, inhibits sebaceous gland function and keratinization, and is used in the treatment of severe inflammatory acne but is contraindicated in pregnancy because of its implication as a cause of birth defects.