hypofunctional en · ADJ
Etymology
From hypo- + functional.
Meanings
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(not-comparable) Having a decreased function (especially of an endocrine gland)
Support for the hypofunctional (as opposed to activated) microglia model is largely based on morphological examination of IBA1-stained microglia in autopsy samples from aged humans [ 29 – 32 ], as currently there are no specific markers that recognize only degenerating/dystrophic microglia.
2015 May 23, Adam D. Bachstetter et al., “Disease-related microglia heterogeneity in the hippocampus of Alzheimer’s disease, dementia with Lewy bodies, and hippocampal sclerosis of aging”, in Acta Neuropathologica Communications, volume 3, →DOI: