hepcidin en · NOUN
Etymology
From hep(ato)- (“liver”) + -cide (“killing”) + -in (“compound”), because of its origin and bacteria-killing properties.
Meanings
-
(uncountable, usually) A hormone produced by the liver that regulates iron homeostasis in mammals.
The known genetic defects of iron metabolism 14, 25, 26 frequently involve proteins that function as iron transporters/exporters (for example, ferroportin 18), as receptors for iron-binding proteins (for example, transferrin receptor 27 and hemochtomatosis 28), or to regulate the activity of these transporters or receptors (for example, hepcidin 29).
2008 November 26, Masako Kohyama, Wataru Ise, Brian T. Edelson, Peter R. Wilker, Kai Hildner, Carlo Mejia, William A. Frazier, Theresa L. Murphy, Kenneth M. Murphy, “Role for Spi-C in the development of red pulp macrophages and splenic iron homeostasis”, in Nature, volume 457, number 7227, →DOI:
Forms
| Spelling | Features | Labels | Source |
|---|---|---|---|
| hepcidins | Number=Plur | lexicographic |
Deriveds
Relateds
ferritin · ferroportin · transferrin
Translations (1)
it epcidina (Translations)