helix-loop-helix en · NOUN
Etymology
From helix + loop + helix. The term got its name from its distinct physical geometry; two alpha helices separated and connected by a flexible chain of amino acids known as a "loop", allowing the helices to pack together tightly.
Meanings
- A structural motif where two alpha helices are connected by a highly flexible amino acid loop, allowing the helices to pack together. Usually requires forming a dimer with another HLH protein before binding DNA.
Forms
| Spelling | Features | Labels | Source |
|---|---|---|---|
| HLH | Abbr=Yes | lexicographic | |
| helix-loop-helices | Number=Plur | lexicographic |
Relateds
zinc finger · homodimerization · helix-turn-helix · heterodimerization · leucine zipper · myogenesis