great-pox en · NOUN
Meanings
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(obsolete, uncountable) Syphilis.
Putting aside passages which might possibly apply to great-pox, smallpox was evidently well known to Shakespeare and his contemporaries.
1898, Thomas Stevenson, A treatise on hygiene and public health, volume 2, page 890:
Forms
| Spelling | Features | Labels | Source |
|---|---|---|---|
| great pox | alternative | lexicographic | |
| greatpox | alternative | lexicographic | |
| Great Pox | alternative | lexicographic |