frameshift en · NOUN
Etymology
From frame + shift.
Meanings
- (countable, uncountable) A frameshift mutation.
Forms
| Spelling | Features | Labels | Source |
|---|---|---|---|
| frameshifts | Number=Plur | lexicographic |
Dictionary
Words, grammatical forms and meanings linked to the ontology.
frameshift en · VERB
Etymology
From frame + shift.
Meanings
-
To use a starting point for translating a series of nucleotides that is off by an amount not divisible by three, resulting in an entirely distinct set of codons.
Considering these costs, it seems likely that mechanisms may exist to stop frameshifted translation as soon as possible, depending on the frequency of occurrence.
2004, DNA and Cell Biology - Volume 23, page 702:Commonly, there are stimulatory signals in mRNA distinct from the shift site that greatly increase the level of frameshifting at the shift site.
2003, Jacques Lapointe, Lea Brakier-Gigras, Translation Mechanisms, →ISBN, page 354:Ribosomal frameshifting at a particular site can yield two protein products from one coding sequence or one protein product from two overlapping open reading frames.
2006, De-Shuang Huang, George William Irwin, Computational Intelligence and Bioinformatics, →ISBN:
Forms
| Spelling | Features | Labels | Source |
|---|---|---|---|
| frameshifted | Tense=Past, VerbForm=Part | lexicographic | |
| frameshifted | Tense=Past | lexicographic | |
| frameshifting | Tense=Pres, VerbForm=Part | lexicographic | |
| frameshifts | Number=Sing, Person=3, Tense=Pres | lexicographic |