flox en · VERB · etymology 1
Pronunciation
- (Southern-England) audio
- /flɒks/ (Received-Pronunciation)
- /flɑks/ (General-American)
Etymology
Abbreviation of "flanked by loxP"
Meanings
-
(qualifier:molecular biology) To sandwich a DNA sequence between two recombinase binding sequences such as "loxP".
Technically, the main problems encountered are in floxing the target gene.
2007, Curt D. Sigmund, David E. Stec, “Genetic Manipulation of the Renin-Angiotensin System Using Cre-loxP-Recombinase”, in Donna H. Wang, editor, Angiotensin Protocols, →ISBN, page 62:In order to do this, the gene to knock out must first be floxed by homologous recombination.
2003, Louis-Marie Houdebine, Animal Transgenesis and Cloning, →ISBN, page 93:
Forms
| Spelling | Features | Labels | Source |
|---|---|---|---|
| floxes | Number=Sing, Person=3, Tense=Pres | lexicographic | |
| floxing | Tense=Pres, VerbForm=Part | lexicographic | |
| floxed | Tense=Past, VerbForm=Part | lexicographic | |
| floxed | Tense=Past | lexicographic |
Deriveds
Relateds
Quinolone antibiotic on Wikipedia. for the nickname for severe reactions to quinolone antibiotics.