Dictionary

enzymogenesis en · NOUN

Etymology

From enzyme + -o- + -genesis.

Meanings

1. The evolutionary development of function of an enzyme, typically used for alcohol dehydrogenases.
   • This multiple enzymogenesis of the same activity from different superfamilies is again analogous to the situation for ADHs and PDHs, where different forms belong to either of these two superfamilies. 2008, B. Persson, J. Hedlund, H. Jörnvall, “Medium- and short-chain dehydrogenase/reductase gene and protein families”, in Cellular and Molecular Life Sciences, →DOI:
   • Hence, the two cod enzyme structures define the earlier events and illustrate the "enzymogenesis," or emergence of a unique enzyme. 1992, Olle Danielsson, Hans Jörnvall, “"Enzymogenesis": classical liver alcohol dehydrogenase origin from the glutathione-dependent formaldehyde dehydrogenase line”, in Proc Natl Acad Sci U S A, →DOI, page 9250:
   • On the supposition that these ADH families might have evolved in response to ethanol exposure, the possibility that ethanol triggered enzymogenesis within each ADH family will be discussed in the sections that follow. 2011, Aída Hernández-Tobías, Adriana Julián-Sánchez, Enrique Piña, Héctor Riveros-Rosas, “Natural alcohol exposure: is ethanol the main substrate for alcohol dehydrogenases in animals?”, in Chem Biol Interact, →DOI:

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