Dictionary

cholangioprotective en · ADJ

Pronunciation

• /kəˌlændʒi.oʊ.prəˈtɛk.tɪv/
• /koʊˌlændʒi.oʊ.prəˈtɛk.tɪv/

Etymology

From cholangio- + protective.

Meanings

1. The property of protecting the bile ducts (cholangiocytes) from damage, disease, or dysfunction. It is used in medical and pharmacological contexts to describe substances, therapies, or mechanisms that help maintain the health of the biliary system.
   • Nonamidated norUDCA undergoes cholehepatic shunting enabling 'ductular targeting' and inducing a bicarbonate-rich hypercholeresis, with cholangioprotective effects. 2015, Trauner M, Halilbasic E, Claudel T, Steinacher D, Fuchs C, Moustafa T, Pollheimer M, Krones E, Kienbacher C, Traussnigg S, Kazemi-Shirazi L, Munda P, Hofer H, Fickert P, Paumgartner G, “Potential of nor-Ursodeoxycholic Acid in Cholestatic and Metabolic Disorders.”, in Digestive diseases, volume 33, number 3, Basel, Switzerland, page 433:
   • Agonism of these receptors exerts important cholangioprotective and anti-inflammatory effects. 2023, Petar Mamula, Judith R. Kelsen, Andrew B. Grossman, Robert N. Baldassano, Jonathan E. Markowitz, editors, Pediatric Inflammatory Bowel Disease, 4 edition, Springer Nature, page 131:

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