bitopic en · ADJ
Etymology
From bi- + topic.
Meanings
-
(not-comparable, of a protein) That links two separate domains
However, allosteric biased ligands may confer functional selectivity by exploiting the recently solved extracellular vestibule [50 ] to generate noncompetitive negative or positive allosteric modulators [51 ] or bitopic ligands [52 ].
2015 October 31, “Receptor, Ligand and Transducer Contributions to Dopamine D2 Receptor Functional Selectivity”, in PLOS ONE, →DOI: