antiresorptive en · ADJ
Etymology
From anti- + resorptive.
Meanings
-
Inhibiting resorption.
Although developed as antiresorptive agents, several compounds show lysosomotropic effects, cutaneous adverse effects and anabolic activity, which are intrinsically related to the selectivity of inhibitors toward CatK. Therefore, alternative compounds having better selectivity toward CatK may complement the use of CKIs in bone resorption therapy.
2015 July 14, “Azanitrile Cathepsin K Inhibitors: Effects on Cell Toxicity, Osteoblast-Induced Mineralization and Osteoclast-Mediated Bone Resorption”, in PLOS ONE, →DOI:
Forms
| Spelling | Features | Labels | Source |
|---|---|---|---|
| most antiresorptive | Degree=Sup | lexicographic | |
| more antiresorptive | Degree=Cmp | lexicographic |