Dictionary

alkoxycyclization en · NOUN

Etymology

Etymology tree Akkadian 𒎎𒋆𒁉𒍣𒁕 (guḫlum)bor. Aramaic כוחלא (kuḥlā)bor. Arabic كُحْل (kuḥl) Andalusian Arabic كُحُول (kuḥūl)bor. Medieval Latin alcoholbor. Middle English alcofol English alcohol English alk- Proto-Indo-European *h₂eḱ-der.? Ancient Greek ὀξύς (oxús) Proto-Indo-European *ǵenh₁- Proto-Indo-European *-os Proto-Indo-European *ǵénh₁os Proto-Hellenic *génos Ancient Greek γένος (génos) French oxygènebor. English oxygen English -oxy English alkoxy Proto-Indo-European *kʷelh₁-redup. Proto-Indo-European *-os Proto-Indo-European *kʷékʷlos Proto-Hellenic *kʷókʷlos Proto-Hellenic *kúklos Ancient Greek κῠ́κλος (kŭ́klos)der. Late Latin cyclusbor. Middle English cicle English cycle Proto-Indo-European *-id- Proto-Indo-European *-yéti Proto-Indo-European *-idyéti Proto-Hellenic *-íd͏̌d͏̌ō Ancient Greek -ῐ́ζω (-ĭ́zō)bor. Late Latin -izōder. Middle French -iserbor. Middle English -isen English -ize English cyclize Proto-Indo-European *-tis Proto-Indo-European *-Hō Proto-Indo-European *-tiHō Proto-Italic *-tiō Latin -tiō Latin -ātiōlbor. Old French -ationbor. Middle English -acioun English -ation English cyclization English alkoxycyclization From alkoxy + cyclization.

Meanings

1. A reaction in which the addition of an alkoxy group to one carbon atom of a double or triple bond is accompanied by cyclization
   • A transition state similar to TS 34 – 33 has been proposed in the reaction of cyclopropyl gold(I) carbenes generated by retro-Buchner reaction of 7-cyclopropyl 1,3,5-cycloheptatrienes. 79 Gold(I) complexes are able to catalyze the addition of amines, alcohols, or water to 1, n -enynes affording products of amino-, alkoxy-, or hydroxycyclization under much milder conditions than other metal catalysts. 26, 32, 33, 62, 80 − 82 These additions are stereospecific, as illustrated by the alkoxycyclization of diastereomeric enynes 1m and 1h, and proceed via opening of cyclopropyl gold(I) carbene intermediates 35 by attack of the nucleophile to the cyclopropane ring (Scheme 11 ). 2015 June 10, Ruth Dorel, Antonio M. Echavarren, “Gold-Catalyzed Reactions via Cyclopropyl Gold Carbene-like Intermediates”, in The Journal of Organic Chemistry, volume 80, →DOI:

Forms