Haldane's rule en · PROPN
Etymology
Formulated in 1922 by the British evolutionary biologist J. B. S. Haldane.
Meanings
-
An observation about the early stage of speciation, stating that if in a species hybrid only one sex is inviable or sterile, that sex is more likely to be the heterogametic sex.
One study hints at the possibility that Haldane's rule may have been the cause of the lack of Neanderthal DNA on the Y-chromosome of hybrids, but currently we do not definitively know.
2018, Tim Flannery, Europe: The First 100 Million Years, Penguin, published 2019, page 181: