Notably, mouse lines targeting genes codifying for serotonin receptors, for enzymes involved in 5-HT synthesis as Tph1 and Tph2, in its metabolism as monoaminoxidase A (MAOA) or in its re-uptake as serotonin transporter (SERT), have been generated. 2015 August 21, “Generation of a Tph2 Conditional Knockout Mouse Line for Time- and Tissue-Specific Depletion of Brain Serotonin”, in PLOS ONE, →DOI: